Page 72 - 《食品科学技术学报》2020年第5期

第 38 卷 第 5 期摇 摇 摇 摇 刘摇 伟等: 生物活性多甲氧基黄酮羧酸和氨基酸衍生物的合成及其结构表征 6 7

图 15摇 川陈皮素鄄3鄄O鄄乙酰苯丙氨酸甲酯(14)核磁图谱
Fig. 15摇 NMR spectra of nobiletin鄄3鄄O鄄acetylphenylalanine methyl ester(14)
摇
件下,分别与两种不同的氨基酸甲酯盐酸盐发生缩 [7]摇 LI S M, SANG S M, PAN M H. Anti鄄inflammatory pro鄄
合反应,合成得到橘皮素和川陈皮素的氨基酸甲酯 perty of the urinary metabolites of nobiletin in mouse[J].
衍生物,再经水解反应,合成了 4 种水溶性的多甲氧 Bioorganic and Medicinal Chemistry Letters, 2007, 17
基黄酮氨基酸衍生物(化合物 3 至化合物 6)。 并对 (18): 5177 - 5181.
[8]摇 黄明发, 苏学素, 焦必宁, 等. 柑橘多甲氧基黄酮的
所合成的化合物进行了结构表征。 该合成方法原料
检测及分离纯化技术研究进展[J]. 食品科学, 2009,
易得、工艺简便、收率较高,具有较高的实用价值。
30 (1): 275 - 280.
HUANG M F, SU X S, JIAO B N, et al. Research pro鄄
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