Page 66 - 《食品科学技术学报》2020年第4期
P. 66

第 38 卷 第 4 期摇 摇 摇 摇 摇 摇 步摇 营等: 基于分子对接技术从虾夷扇贝中筛选抗 SARS鄄CoV鄄2 活性肽研究                             6 1


         novel coronavirus from the ongoing Wuhan outbreak and  MA J, HUO X Q, CHEN Q, et al. Study on screening
         modeling of its spike protein for risk of human transmis鄄  Chinese traditional medicine against SARS鄄CoV鄄2 based
         sion[J]. Science China Life Sciences, 2020, 63(3):  on Mpro and PLP[J]. China Journal of Chinese Materia
         457 - 460.                                        Medica, 2020, 45(6):1219 - 1224.
   [11] 摇 LI Y, ZHANG J Y, WANG N, et al. The rapeutic  [16]摇 宗阳, 丁美林, 贾可可, 等. 基于网络药理学和分子
         drugs targeting 2019鄄nCoV main protease by high鄄  对接法探寻达原饮治疗新型冠状病毒肺炎(COVID鄄
         throughput screening[ J/ OL]. bioRxiv, 2020. [2020鄄  19)活性化合物的研究[J]. 中草药, 2020, 51(4):
         06鄄08]. https:椅doi. org/ 10.1101/ 2020.01.28.922922.  836 - 844.
   [12]摇 莫立乾, 郑萍. 新型冠状病毒肺炎治疗药物:磷酸氯                         ZONG Y, DING M L, JIA K K, et al. Exploring the
         喹[J]. 南方医科大学学报, 2020, 40(4): 586 - 594.           active compounds of Da鄄Yuan鄄Yin in treatment of novel
         MO L Q, ZHENG P. Chloroquine phosphate: the       coronavirus (2019鄄nCoV) pneumonia based on network
         rapeutic drug for COVID鄄19 [ J]. Journal of Southern  pharmacology and molecular docking method[J]. Tradi鄄
         Medical University, 2020, 40(4): 586 - 594.       tional and Herbal Drugs, 2020, 51(4):836 - 844.
   [13]摇 孙逊, 陶嘉磊, 许少菊, 等. 基于网络药理学探究化                 [17]摇 YU Z P, WU S J, ZHAO W Z, et al. Identification and
         湿败毒方治疗新型冠状病毒肺炎的分子机制[J/ OL].                       the molecular mechanism of a novel myosin鄄derived ACE
         中药材, 2020. [2020鄄06鄄08]. http:椅kns. cnki. net/    inhibitory peptide [J]. Food & Function, 2018, 9(1):
         kcms/ detail/ 44.1286. R.20200430.1759.006. html.  364 - 370.
         SUN X, TAO J L, XU S J, et al. The molecular mecha鄄  [18]摇 TIAN X L, LI C, HUANG A L, et al. Potent binding of
         nism of treating COVID鄄19 with Huashi Baidu formula  2019 novel coronavirus spike protein by a SARS corona鄄
         based on network pharmacology [ J/ OL]. Journal of  virus鄄specific human monoclonal antibody [ J]. Emerg
         Chinese Medicinal Materials, 2020. [ 2020鄄06鄄08 ].  Microbes Infect, 2020, 9(1): 382 - 385.
         http:椅kns. cnki. net/ kcms/ detail/ 44. 1286. R. 20200430.  [19]摇 LEI C H, FU W Y, QIAN K W, et al. Potent neutral鄄
         1759.006. html.                                   ization of 2019 novel coronavirus by recombinant ACE2鄄
   [14]摇 邓燕君, 刘博文, 贺桢翔, 等. 基于网络药理学和分                       Ig [ J/ OL]. bioRxiv,2020. [2020鄄06鄄08]. https:椅
         子对接法探索藿香正气口服液预防新型冠状病毒肺                            www. biorxiv. org/ content/ 10.1101/ 2020.02.01.929976v2.
         炎(COVID鄄19)活性化合物研究[J]. 中草药, 2020,           [20]摇 LIU X, WANG X J. Potential inhibitors for 2019鄄n CoV
         51(5):1113 - 1122.                                coronavirus M protease from clinically approved medi鄄
         DENG Y J, LIU B W, HE Z X, et al. Study on active  cines [J/ OL]. bioRxiv, 2020. [2020鄄06鄄08]. https:椅
         compounds from Huoxiang Zhengqi oral liquid for pre鄄  www. biorxiv. org/ content/ 10.1101/ 2020.01.29.924100v1.
         vention of coronavirus disease 2019 (COVID鄄19) based  [21]摇 沈亮亮, 李勇, 周明, 等. 基于分子对接技术筛选抗
         on network pharmacology and molecular docking [ J].  严重急性呼吸综合征冠状病毒 2 中药小分子化合物
         Chinese Traditional and Herbal Drugs, 2020, 51(5):  [J]. 中国新药杂志, 2020, 29(7):773 - 781.
         1113 - 1122.                                      SHEN L L, LI Y, ZHOU M, et al. Screening of anti鄄
   [15]摇 马婧,霍晓乾,陈茜,等. 基于 Mpro 和 PLP 筛选潜在                   SARS鄄CoV鄄2 small molecular compounds from traditional
         抗新型冠状病毒中药研究[J]. 中国中药杂志,2020,                      Chinese medicine based on molecular docking[J]. Chi鄄
         45(6):1219 - 1224.                                nese Journal of New Drugs, 2020, 29(7):773 - 781.

               Screening Research of Anti鄄SARS鄄CoV鄄2 Peptides from
                 Mizuhopecten yessoensis Based on Molecular Docking


                         1          1            1,2             1,*             1
                  BU Ying ,摇 HE Wei ,摇 WANG Fei ,摇 ZHU Wenhui       ,摇 LI Xuepeng ,摇
                                         1             1            1,*
                                YI Shumin ,摇 XU Yongxia ,摇 LI Jianrong
      (1. College of Food Science and Technology, Bohai University / National & Local Joint Engineering Research
       Center of Storage, Processing and Safety Control Technology for Fresh Agricultural and Aquatic Products/
          National R&D Branch Center of Surimi and Surimi Products Processing, Jinzhou 121013, China;
            2. Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University,
                                         Dalian 116034, China)

       Abstract: In order to screen bioactive peptides against SARS鄄CoV鄄2 from food raw materials,
   61   62   63   64   65   66   67   68   69   70   71