Obesity is one of the worldwide concerned chronic diseases, which is a risk factor of cardiovascular and cerebrovascular diseases, cancer and other diseases. It has become the most important health problem threatening human. Most of the existing weight-loss drugs or methods have the disadvantages of great toxic and side effects and easy to rebound. Therefore, it is of great significance to seek safe and effective drugs or methods to intervene obesity. Natural plant extracts including anthocyanins have effective intervention on obesity with little side effects. Lycium ruthenicum Murr. is one of the newly discovered edible plant resources in recent years. It has a variety of biological activities, such as reducing blood lipid, anti-oxidation, anti-mutation, anti-cancer, anti-inflammation, improving immunity and so on. Differing with others from common fruits and vegetables, the characteristic structure of anthocyanins from Lycium ruthenicum Murr. is containing parent nucleus of petunia and aromatic acid acylation. And the total content of the anthocyanins is much higher than other colored fruits. In this paper, the research progress of the effect of anthocyanins in Lycium ruthenicum Murr. on intervention of obesity was reviewed by summarizing the relevant references, which provided theoretical references for the development and utilization of Lycium ruthenicum Murr..