In order to investigate the migration of plasticizer from PVC wrap to pork, a method for determination of nine plasticizers in pork by gas chromatography coupled with solid-phase extraction was deve-loped. The contents and migration behaviors of plasticizers in PVC wrap were analyzed by using the established method. The results showed that the limits of detection (LOD, S/N=3) for nine kinds of plasticizer were ranged from 0.020 mg/kg to 0.036 mg/kg, which could meet the need of analysis. Di (2-ethylhexyl) phthalate (DEHP) and di (2-ethylhexyl) adipate (DEHA) were detected in PVC wrap obtained from the market. The migrating of DEHP and DEHA from PVC wrap to pork was studied. In the migration experiment, the quantity of migration was influenced by temperature, contact time, and fat contents of pork. In a certain range, the increasing of temperature, contact time, and fat contents led to a larger migration. For thin packaging materials, the result of single-side migration test was closer to the actual situation. The experimental data could predict the safety of plasticizers in food packaging materials and prepackaged foods.