With the increase of age, the prevalence rate of osteoporosis and fracture caused by osteoporosis and osteoarthritis is gradually increasing.Early prevention and intervention are the measures to fundamentally solve the problem and prevention is better than cure. Nutritional intervention is the supplement and update of the traditional osteoarthritis treatment method. In addition to lifestyle intervention, nutritional intervention plays an important role in balancing anabolic and catabolic metabolism of bone and cartilage tissues and metabolism, and regulating immune responses. Moreover, nutrition intervention has many advantages, such as less side effects and lower cost, which is easy to get some nutrients in the diet every day.Research progress on bone nutrition supplements, including whole bone nutrition, glucosamine and chondroitin sulfate, collagen peptide etc, were reviewed. We hope that this work can provide useful reference for related researches.