Whole egg liquid is rich in protein, fat, and many kinds of vitamins and minerals. It is a natural source of nutritional supplements, but high level of phosphorus limits its use in the diet of patients with kidney disease. Activated carbon, hydrotalcite and diatomite were selected to dephosphorize the whole egg liquid. The dephosphorization rate, protein loss rate and color difference changes were taken as the indexes, the optimum amount of adsorbent, adsorption time and adsorption temperature were optimized, and then, the adsorption isotherms, adsorption kinetics and adsorption thermodynamics of phosphorus adsorption by three adsorbents in the whole egg liquid were fitted. The results showed that the optimum dosage of activated carbon was 8g/L, adsorption time was 120min and adsorption temperature was 35℃, while the optimum dosage of hydrotalcite was 8g/L, adsorption time was 150min and adsorption temperature was 35℃, and the optimum dosage of diatomite was 8g/L, the adsorption time was 90min and the adsorption temperature was 35℃. In the process of adsorption, hydrotalcite led to the least loss of protein and the highest adsorption specificity for phosphate groups. Activated carbon had the greatest effect on a*, diatomite had the greatest effect on b*, and all three adsorbents increased L*. The study of adsorption mechanism showed that diatomite was adsorbed in the form of monolayer, and n value of Freundlich adsorption isotherm of three adsorbents were all greater than 1. With the increase of adsorption temperature, the KF of activated carbon, hydrotalcite and diatomite increased gradually. The quasi-first-order kinetic model R² of three adsorbents were lower, and fluctuated with the increase of temperature. The quasi-second-order kinetic model R² of diatomite was higher, and the chemical adsorption degree of diatomite was higher. The ΔG of activated carbon, hydrotalcite and diatomite were all negative and the ΔH were greater than 0, which meant that the reaction was spontaneous and endothermic.