The contents of total phenols, total flavonoids, anthocyanins and mineral elements in different parts of pomelo were determined, and the correlation between polyphenols contents and antioxidant activities, such as reduction ability, OH and DPPH radical scavenging ability were explored. The results showed that the total phenols content of each parts of pomelo in descending order were yellow peel, white peel,capsule dressing, pulp, and pomelo seed and the total phenols content in yellow peel was 12.68mg/g. The contents of total flavonoids in different parts were as follows:capsule dressing > pomelo seed > white peel > yellow peel > pulp, which was 1.146mg/g in capsule dressing. The highest content of anthocyanins was found in pulp. Pomelo was rich in K, Ca, Mg, Mn, Na, Fe and other elements. And the mineral elements were mainly concentrated in yellow peel, while were hardly detected in white peel. The reduction abilities of alcohol extracts in different parts of pomelo were as follows:yellow peel > pulp > pomelo seed > white peel > capsule dressing. The scavenging rates of ·OH were as follows:yellow peel > capsule dressing > white peel > pomelo seed > pulp. Alcohol extracts of capsule dressing had the highest scavenging rate of DPPH radical (95.24%). Correlation analysis indicated that, the content of total polyphenols, total flavonoids and anthocyanins had no significant correlations with reducing ability or scavenging rate of DPPH radical(P>0.05), while total polyphenols contents were significantly associated with scavenging rate of OH radical(P<0.05). The content of K, Ca, and Mg had highly significant positive correlations with reducing ability and scavenging rate of OH radical(P<0.01), but no significant correlation with scavenging rate of DPPH radical(P>0.05).