The equipment structure and characteristics of ultrasonic extraction circulation were intro-duced based on the advantages and disadvantages of domestic ultrasonic extraction equipment. A set of continuous cyclic ultrasonic extraction production line was designed combined with cycle ultrasonic extraction technology. Material packaging system, material conveying system, ultrasonic extraction system, extracting enrichment system, and recovery system were included in this production line. According to the dynamic relationship of ultrasonic extraction of active ingredients from plant resources, the reasonable process parameters were set, and actual production data were obtained. Meanwhile, the advantage of the production line was compared with other ultrasonic extraction device.