The pesticide application and control system of residues in the United Nations, the United States, the European Union, Japan and other international organizations were reviewed in this paper. The situation of the pesticides application and residue control system of the international organizations and the developed countries were summarized. The development trend of residual control system was analyzed. The pesticides application and residue control situation in China was also introduced. Some suggestions on system, measures, and standard to strengthen our country’s control on pesticides use and residues control was proposed.